Guest Editorial: Biomedical Informatics in Clinical Environments The aim of this special section is to provide an overview of the emerging biomedical informatics technologies and their application in research and clinical environments. Recent developments inbiomedical informatics have created methods, techniques and tools, which are based on the analysis of heterogeneous data, data mining, decision support systems, multiscale modeling, etc. The distance from the development of such systems and the real clinical environments is still long enough, and only some of them have been used in a clinical scale.