Iterative Cancellation of Non-Linear Distortion Noise in Digital Communication Systems In this paper, an iterative receiver that performs non-linear distortion noise cancellation is presented. The performance is assessed for time division multiple access (TDMA), orthogonal frequency division multiple access (OFDMA) and single-carrier frequency division multiple access (SC-FDMA) waveforms. Even though a return link setup is considered, the receiver is equally applicable in the forward link, taking into account the differences in the data multiplexing and the channel. Analytical modeling of the received electrical signal-to-noise ratio (SNR) is carried out for OFDMA with one iteration of non-linear distortion noise cancellation. The performance is assessed in terms of power efficiency and spectral efficiency, where the total degradation (TD) of the received SNR in a non-linear channel is minimized. The modulation formats of the DVB-RCS2 satellite return link standard and a respective non-linear channel have been used. OFDMA shows the highest power efficiency gain of 1.1-2.5 dB with 2 iterations of non-linear noise cancellation across the different modulation orders. In SC-FDMA, the gain is in the range of 0.3-1.1 dB, while gains of 0.1-0.8 dB and 0.2-1.9 dB are presented in TDMA with 20% roll-off and 5% roll-off, respectively.